The autonomic nervous system is the other division of the human nervous system, which is in charge of most of the automatic processes in the body including heartbeat, digestion, breathing, dilation of the pupils, constriction of pupils, ejaculation, and micturition. This work focuses on the relations and mediators implied in these functions and on the principal regulatory models. Both sympathetic and parasympathetic systems are essential in creating flexibility, and whenever a shift occurs, many health issues may develop as a result. (...) For instance, an ANS activity level too high will cause hypertension or heart issues, while an ANS activity level too low will cause anxiety or panic disorders. The review also discusses the impact of ANS and other new advancements in genetics and genetic makeup regarding stress responsiveness. Even though some people’s genetic predisposes them to certain ANS disorders they can be faced with it due to their lifestyle and stress. Nevertheless, concise information is still scarce about ANS, underlining the importance of further research to evaluate pathogenic genes, and constituent the genetic treatments to enhance the disease's negative outlook. (shrink)

1. Introduction -- 2. Philosophy of genetic technology and its relation to ethical theories -- 3. Ethics of genetic technology in plants and animals -- 4. Ethics of genetic technology in humans -- 5. Conclusion.

This article expands Kandiyoti's concept of patriarchal bargaining to include men's negotiations. It analyzes how marginalized groups within a dominant sociocultural knowledge regime strategize to advance change while trying to maximize security and optimize their life options. The case study analyzes primaries held within kin-based groupings— hamulas among Palestinian Arabs in Israel—to determine the candidates for municipal elections. Based on interviews and analysis of newspaper articles, the authors claim that the turn to primaries by hamulas was an attempt to resolve (...) disputes that were undermining the patriarchal system. The primaries provided entry to those of lower ranking in the hierarchy of hamula political leadership, while retaining the exclusion of women from the political sphere. Thus, while bargaining with patriarchy, gender identities and hierarchies are contested, re/produced, and negotiated as both a political means and an anchor for social identities. (shrink)

BackgroundNational Ethics Committees (NECs) offer important oversight and guidance functions and facilitate public debate on bioethical issues. In an increasingly globalized world where technological advances, multi-national research collaborations, and pandemics are creating ethical dilemmas that transcend national borders, coordination and the joining of efforts among NECs are key. The purpose of this study is to take stock of the current NEC landscape, their varying roles and missions, and the range of bioethical topics on which they deliberated since their inception.MethodsData on (...) the availability, functions, and ethical deliberations (publications) of NECs globally were gathered through a systematic search of NEC websites and through contacts known to the authors. The search was conducted in English, French, and Spanish. The data abstraction was done in Excel and included the NEC’s country, region, functions, and deliberations on bioethical issues. Deliberation topics were classified into thematic categories through an iterative process of regrouping to arrive at the main set of themes.Results124 NECs in 100 countries were identified. 44% of the NECs are in Europe and 47% are in high-income countries. Out of the 1108 retrieved publications, 40% were on bioethics in the context of research, followed by the clinic (28%) and public health issues (22%). The top five topics of these publications were: research ethics (124; 9%), genetics and genomics (62; 6%), organ transplantation (58; 5%), assisted reproductive technology (49; 4%), and end of life (36; 3%).ConclusionOur study makes an important contribution to understanding the current interests and functions of NECs and the range of their bioethics deliberations. By making the data publicly available through this publication, it allows users to conduct tailored analyses and queries based on their interests, and to seek and strengthen collaboration and exchange. It also makes the case for the fruitfulness of developing and maintaining a global repository of current and new deliberations to more effectively advance this field for the greater good of humanity, research, and public health. (shrink)

The big five personality traits and entrepreneurial mindset are crucial individual-level elements that determine entrepreneurial intention. This study examines the impact of big five personality traits and EM, on EI using the theory of planned behavior. Besides, this study examined the role of entrepreneurial self-efficacy and attitude toward entrepreneurship influences EI. To achieve the research objectives, a quantitative approach was used. Structural equation modeling and path analysis were conducted using SmartPLS software. Data were collected from 270 respondents through online questionnaires. (...) Findings of the study revealed that big five personality traits influence ESE and ATE which led to EI. Finally, the moderating role of entrepreneurial passion was also found to have strong effect on influence ESE and ATE. This study offers evidence and insights that academics, educators, and others involved in the creation or expansion of entrepreneurial knowledge can use as a reference point. (shrink)

In this article, we consider estimation of the parameters of a generalized Pareto distribution and some lifetime indices such as those relating to reliability and hazard rate functions when the failure data are progressive first-failure censored. Both classical and Bayesian techniques are obtained. In the Bayesian framework, the point estimations of unknown parameters under both symmetric and asymmetric loss functions are discussed, after having been estimated using the conjugate gamma and discrete priors for the shape and scale parameters, respectively. In (...) addition, both exact and approximate confidence intervals as well as the exact confidence region for the estimators are constructed. A practical example using a simulated data set is analyzed. Finally, the performance of Bayes estimates is compared with that of maximum likelihood estimates through a Monte Carlo simulation study. (shrink)

Textbook Islam, nation building, and the question of violence / Gregory Starrett and Eleanor Abdella Doumato -- Egypt : promoting tolerance, defending against Islamism / James A. Toronto and Muhammad S. Eissa -- Iran : a Shi'ite curriculum to serve the Islamic state / Golnar Mehran -- Jordan : prescription for obedience and conformity / Betty Anderson -- Kuwait : striving to align Islam with Western values / Taghreed Alqudsi-Ghabra -- Oman : cultivating good citizens and religious virtue / (...) Mandana E. Limbert -- The Palestinian national authority : the politics of writing and interpreting curricula. Genesis of a new curriculum / Nathan Brown ; A conflict of historical narratives / Seif Da'Na -- Saudi Arabia : from "Wahhabi" roots to contemporary revisionism / Eleanor Abdella Doumato -- Syria : secularism, Arabism, and Sunni orthodoxy / Joshua Landis -- Turkey : sanctifying a secular state / Ozlem Altan -- Textbook meanings and the power of interpretation / Gregory Starrett -- Conclusion : tailor-made Islam / Eleanor Abdella Doumato and Gregory Starrett. (shrink)